Related Experiment Video

Updated: Jun 10, 2026

Application of Aorta-gonad-mesonephros Explant Culture System in Developmental Hematopoiesis
07:38

Application of Aorta-gonad-mesonephros Explant Culture System in Developmental Hematopoiesis

Published on: November 3, 2017

Developmental hematopoiesis: historical background and perspectives. An interview with Nicole le Douarin. Interview

Nicole le Douarin

    The International Journal of Developmental Biology
    |August 17, 2010
    PubMed

    More Related Videos

    Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells14:37

    Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells

    Published on: November 1, 2017

    In Vitro Model of Fetal Human Vessel On-chip to Study Developmental Mechanobiology09:12

    In Vitro Model of Fetal Human Vessel On-chip to Study Developmental Mechanobiology

    Published on: July 28, 2023

    Related Concept Videos

    Hematopoiesis01:21

    Hematopoiesis

    The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
    Overview of Hematopoiesis01:20

    Overview of Hematopoiesis

    Hematopoiesis, or blood cell production, is a vital biological process that begins early in embryonic development and continues throughout life. This process generates the various types of cells found in blood, including red blood cells, white blood cells, and platelets from hematopoietic stem cells (HSCs).
    Developmental Phases of Hematopoiesis
    Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
    Role of Hematopoietic Growth Factors01:28

    Role of Hematopoietic Growth Factors

    Hematopoietic growth factors are molecules that regulate the differentiation rate of hematopoietic stem cells (HSCs). Erythropoietin (EPO), primarily produced by the kidneys, plays a crucial role in erythrocyte production. When oxygen levels in the blood are low, EPO is released into the bloodstream, reaching the bone marrow, where it stimulates HSCs to differentiate and mature into erythrocytes, which are vital for oxygen transport.
    Thrombopoietin (TPO), mainly released by the liver,...
    Regulation of Hematopoietic Stem Cells01:01

    Regulation of Hematopoietic Stem Cells

    All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
    Multipotency of Hematopoietic Stem Cells01:19

    Multipotency of Hematopoietic Stem Cells

    The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
    Lineage Commitment01:21

    Lineage Commitment

    Commitment is the  process whereby stem cells: