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Updated: Jun 10, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
Multiple bowel intussusceptions from metastatic localized malignant pleural mesothelioma: a case report
Hsien Liu1, Yu-Jen Cheng, Hsin-Pao Chen
1Division of Thoracic Surgery, Department of Surgery, E-DA Hospital/I-Shou University, 1 Yi-Da Road, Jiau-shu Tsuen, Yan-chau Shiang, Kaohsiung 824, Taiwan, China.
Localized malignant pleural mesothelioma (LMPM) rarely metastasizes to the gastrointestinal tract. This case highlights intra-luminal metastases in the small intestine and colon following recurrence, emphasizing the need for vigilance.
Area of Science:
- Oncology
- Gastroenterology
- Thoracic Surgery
Background:
- Localized malignant pleural mesothelioma (LMPM) is a rare thoracic malignancy.
- Gastrointestinal intra-luminal metastases from LMPM have not been previously documented.
- Local recurrence is a known complication of LMPM after surgical resection.
Observation:
- A patient with LMPM experienced local recurrence 10 months post-surgery.
- Abdominal CT revealed a "target sign" in the left lower quadrant.
- Laparotomy identified intra-luminal metastatic tumors in the small intestine and colon.
Findings:
- The patient underwent segmental resection of the metastatic lesions.
- Despite surgical intervention, the patient succumbed to sepsis.
Implications:
- This case underscores the potential for distant gastrointestinal metastasis in LMPM.
- Non-specific abdominal pain in LMPM patients warrants thorough investigation for metastasis.
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