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CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
Dexamethasone administration and postoperative bleeding risk in children undergoing tonsillectomy.
Matthew T Brigger1, Michael J Cunningham, Christopher J Hartnick
1Department of Otolaryngology-Head and Neck Surgery, Naval Medical Center San Diego, 34800 Bob Wilson Dr, San Diego, CA 92134. matt.brigger@alumni.vanderbilt.edu
Archives of Otolaryngology--Head & Neck Surgery
|August 18, 2010
Summary
Perioperative dexamethasone in children undergoing tonsillectomy did not increase postoperative hemorrhage risk. Higher doses of dexamethasone (1.0 mg/kg) were not associated with a dose-dependent increase in bleeding complications.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Pharmacology
Background:
- Postoperative hemorrhage is a significant complication following tonsillectomy.
- Dexamethasone is often used perioperatively, but its effect on hemorrhage risk is debated.
Purpose of the Study:
- To determine if perioperative dexamethasone administration is associated with a dose-dependent increase in postoperative tonsillectomy hemorrhage rates in children.
Main Methods:
- Retrospective review of 2788 children and adolescents undergoing tonsillectomy.
- Analysis of hemorrhage rates based on two intravenous dexamethasone doses (0.5 mg/kg vs. 1.0 mg/kg).
- Statistical adjustment for age, sex, diagnosis, and surgical technique.
Main Results:
- Adjusted analysis showed no significant association between higher dexamethasone dose (1.0 mg/kg) and increased hemorrhage risk.
- Odds ratios for any hemorrhage, readmission with operative intervention, or operative intervention alone were not significantly elevated.
Conclusions:
- Perioperative dexamethasone administration is not linked to a dose-dependent rise in postoperative hemorrhage after tonsillectomy in children.
- Findings suggest current dexamethasone dosing protocols are likely safe regarding hemorrhage risk.
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