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Updated: Jun 10, 2026

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Standardized Induction and Assessment of Long-term Potentiation-like Cortical Plasticity Using Transcranial Magnetic Stimulation
Published on: November 7, 2025
Imaging the effects of rTMS-induced cortical plasticity
Charlotte J Stagg1, Jacinta O'Shea, Heidi Johansen-Berg
1Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB), Department of Clinical Neurology, University of Oxford, Oxford, UK. cstagg@fmrib.ox.ac.uk
Restorative Neurology and Neuroscience
|August 18, 2010
Summary
Repetitive Transcranial Magnetic Stimulation (rTMS) shows promise for neurorehabilitation. This review explores how magnetic resonance imaging reveals rTMS
Area of Science:
- Neuroscience
- Neurology
- Psychiatry
Background:
- Repetitive Transcranial Magnetic Stimulation (rTMS) is a promising neurorehabilitation tool.
- Understanding rTMS's cortical modulation mechanisms is crucial.
- Non-invasive brain stimulation techniques are advancing neurorehabilitation.
Purpose of the Study:
- To review magnetic resonance imaging (MRI) findings on rTMS cortical effects.
- To elucidate cellular and network-level changes induced by rTMS.
- To explore rTMS's potential in stroke patient recovery.
Main Methods:
- Review of non-invasive MRI studies on rTMS.
- Analysis of cellular changes in the motor cortex.
- Examination of motor network activation patterns.
Main Results:
- MRI techniques reveal cellular and network effects of rTMS.
- rTMS modulates activation within the motor network.
- Variations in rTMS effects are observed in stroke patients.
Conclusions:
- rTMS mechanisms are increasingly understood through MRI.
- rTMS shows potential for improving function in neurological conditions.
- Further research on stroke patients can optimize rTMS therapy.

