Related Experiment Videos
A new method for labelling of monoclonal antibodies and their fragments with technetium-99m
E Joiris1, B Bastin, J R Thornback
1R/D Imaging, Medgenix Group, Fleurus, Belgium.
A new method of labelling of antibodies with technetium-99m is described. The antibody or fragment is derivatized by iminothiolane. Ligand exchange from a labile technetium complex such as TcO(GLU)2- results in greater than 90% of the technetium labelling the antibody. This method appears to be equally applicable to antibodies and fragments.
A new method of labelling of antibodies with technetium-99m is described. The antibody or fragment is derivatized by iminothiolane. Ligand exchange from a labile technetium complex such as TcO(GLU)2- results in greater than 90% of the technetium labelling the antibody. This method appears to be equally applicable to antibodies and fragments.