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Updated: Jun 10, 2026

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
Graphene field-effect transistors: electrochemical gating, interfacial capacitance, and biosensing applications
Fang Chen1, Quan Qing, Jilin Xia
1Center for Bioelectronics and Biosensors, the Biodesign Institute, Department of Electrical Engineering, Arizona State University, Tempe, AZ 85287, USA.
Abstract:
Single-layer graphene has received much attention because of its unique two-dimensional crystal structure and properties. In this review, we focus on the graphene devices in solution, and their properties that are relevant to chemical and biological applications. We will discuss their charge transport, controlled by electrochemical gates, interfacial and quantum capacitance, charged impurities, and surface potential distribution. The sensitive dependence of graphene charge transport on the surrounding environment points to their potential applications as ultrasensitive chemical sensors and biosensors. The interfacial and quantum capacitance studies are directly relevant to the on-going effort of creating graphene-based ultracapacitors for energy storage.
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