Modular chemosensors from self-assembled vesicle membranes with amphiphilic binding sites and reporter dyes

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Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
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Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Published on: September 10, 2013

Benjamin Gruber1, Stefan Stadlbauer, Andreas Späth

  • 1Institut für Organische Chemie, Universität Regensburg, 93040 Regensburg, Germany.

Angewandte Chemie (International Ed. in English)
|August 18, 2010
PubMed
Abstract

No abstract available in PubMed .

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

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