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Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
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Decomposition-enhanced spike triggered averaging MUNE: validity, reliability, and impact of contraction force

Timothy J Doherty1, Daniel W Stashuk, Shaun G Boe

  • 1Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Centre, London, ON N6A 5A5, Canada. tim.doherty@lhsc.on.ca

Supplements to Clinical Neurophysiology
|August 19, 2010
PubMed
Abstract

No abstract available in PubMed .

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When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
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Muscle Stimulation Frequency01:22

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The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...

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