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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

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Related Experiment Video

Updated: Jun 10, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Scalp psoriasis.

Leon H Kircik1, Sandeep Kumar

  • 1Mount Sinai Medical Center, NewYork, NY, USA. wedoderm@bellsouth.net

Journal of Drugs in Dermatology : JDD
|August 19, 2010
PubMed
Summary
This summary is machine-generated.

New treatments for scalp psoriasis offer improved efficacy and patient compliance. Novel formulations, including calcipotriene/betamethasone scalp solution and coal tar foam, address the unmet need for better scalp psoriasis management.

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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
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SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

Published on: August 8, 2025

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Scalp psoriasis is a chronic, debilitating condition with limited effective treatment options.
  • Current topical therapies often face challenges with application, adherence, and patient satisfaction.
  • There is a significant unmet need for safe, effective, and well-tolerated treatments for scalp psoriasis.

Purpose of the Study:

  • To review the efficacy and safety of new formulations and treatment options for scalp psoriasis.
  • To highlight advancements in managing this common dermatological condition.

Main Methods:

  • Review of new topical formulations for scalp psoriasis.
  • Examination of clinical data on efficacy, safety, and patient compliance.
  • Inclusion of studies on calcipotriene/betamethasone scalp solution, clobetasol propionate shampoo, and coal tar foam.

Main Results:

  • Calcipotriene/betamethasone scalp solution demonstrates a rapid onset of action with once-daily dosing, enhancing compliance.
  • Clobetasol propionate shampoo (0.05%) is reported as safe and efficacious for long-term scalp psoriasis management.
  • A new foam formulation of coal tar is found to be cosmetically acceptable and easier to apply.

Conclusions:

  • Newer treatment options and formulations are emerging for scalp psoriasis.
  • These advancements aim to improve patient adherence and therapeutic outcomes.
  • The reviewed options offer potential for better control and patient satisfaction in managing scalp psoriasis.