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Updated: Jun 10, 2026

Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
Published on: September 22, 2017
[Preparation for cardiopulmonary bypass]
1Division of Cardiovascular Surgery, Cardiovascular Center, Toranomon Hospital, Tokyo, Japan.
Abstract:
This article introduces our standard method of cannulation for extracorporeal circulation. The ascending aorta is used in most operations for arterial cannulation. Bicaval cannulation for venous return is performed through the right atrium. In order to accomplish venting the heart, we introduce a vent catheter to the left atrium through the right superior pulmonary vein. Cardioplegic solution may be administered antegradely through the aortic root or retrogradely through the coronary sinus for myocardial protection. Adequate cardiopulmonary bypass is the key to successful cardiovascular operations.
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