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Updated: Jun 10, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
[A comparison of acetated Ringer's solution and bicarbanated Ringer's solution for fluid therapy during extended
1Department of Anesthesiology and Critical Care Medicine, Hokkaido University Graduate School of Medicine, Sapporo 060-8638.
Background:
We investigated the efficacy of two types of Ringer's solutions, acetated Ringer (AR) and bicarbanated Ringer (BR), during and after high invasive abdominal surgery.
Methods:
We divided 16 patients scheduled for extended hystectomy into 2 groups of AR or BR infusion group. Either AR or BR solution was administered to keep CVP at 2-8 cmH2O and Hb above 7 g x dl(-1) during the entire anesthetic period. Acid base balance, serum magnesium (Mg) and metabolic products such as lactate, pyruvic acid, citric acid, acetoacetic acid and hydroxybutyric acid were measured during and after surgery. IL-6 was determined early on the next morning.
Results:
Metabolic products and IL-6 were not different between the two groups; however, base excess and HCO3- during surgery were kept higher in BR group than in AR group. Intraoperative serum Mg was also maintained higher in BR group.
Conclusions:
From the aspect of the ability to keep acid base balance and Mg level, BR seems to be a more suitable infusion fluid than AR in high invasive abdominal surgery such as extended hystectomy.
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