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Updated: Jun 10, 2026
Murine Cervical Heart Transplantation Model Using a Modified Cuff Technique
Published on: October 12, 2014
A comparative study on suture versus cuff anastomosis in mouse cervical cardiac transplant
Yiming Zhou1, Xiaodong Gu, Jianbin Xiang
1Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Objectives:
To compare the cuff technique to traditional suture technique in establishing cervical heart transplant model in mice.
Materials And Methods:
Eighty transplants were performed by 1 surgeon, 40 using the cuff technique, and 40 using the suture technique, under the same circumstances.
Results:
The cuff approach was significantly superior to conventional suture anastomosis in higher surgical successful rate, less surgery, and less ischemic time (P < .05). Suture anastomosis required an intensive microsurgical training and at least a 16x surgical microscope, while the cuff anastomosis required less learning time and a 10x surgical microscope.
Conclusions:
The cuff technique is the preferred method in cervical heart transplant model in mice.
