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Published on: June 2, 2022
Anesthetic management of children with in situ Berlin Heart EXCOR
Jayant N Pratap1, Sally Wilmshurst
1Department of Anaesthesia, Great Ormond Street Hospital, London, UK. jnpratap@doctors.org.uk
Insights
Pediatric ventricular assist devices (VADs) offer improved outcomes for children awaiting heart transplants. Anesthesiologists must be prepared for VAD-specific emergencies and unique patient care needs.
Area of Science:
- Pediatric Cardiology
- Mechanical Circulatory Support
- Anesthesiology
Background:
- Mechanical devices support children with severe cardiac dysfunction, serving as a bridge to heart transplantation.
- Pediatric heart transplantation improves survival and quality of life but faces donor organ shortages.
- Ventricular assist devices (VADs) show better outcomes than extracorporeal membrane oxygenation as a bridge to transplantation.
Purpose of the Study:
- To highlight the increasing role of anesthesiologists in managing pediatric patients with VADs.
- To discuss the specific considerations for providing anesthesia to children with Berlin Heart EXCOR VADs.
- To outline potential VAD-specific emergencies and their management.
Main Methods:
- Review of current literature on pediatric VADs and anesthesia management.
- Discussion of the Berlin Heart EXCOR system and its application in neonates and children.
- Identification of key anesthetic considerations from preoperative assessment to postoperative care.
Main Results:
- The Berlin Heart EXCOR is a popular VAD system in pediatric practice, available in sizes for neonates.
- Postimplantation care involves managing hemodynamics, preventing thromboembolic complications, and rehabilitation.
- Anesthesiologists must be vigilant for VAD-specific emergencies like dysrhythmias, VAD failure, and embolism.
Conclusions:
- Anesthesia for pediatric patients with Berlin Heart VADs requires specialized preoperative assessment, intraoperative management, and postoperative care.
- Recognition and prompt management of VAD-specific emergencies are crucial for patient safety.
- Preparedness of anesthesiologists is essential given the increasing use of VADs in pediatric cardiac care.
Abstract:
Modern mechanical devices can support children with severely impaired cardiac function until a donor heart is found for transplantation or native function recovers. Pediatric heart transplantation offers a good chance of survival with a high quality of life to individuals with limited life expectancy and/or severe limitation to daily activities, but many die on the transplant list or are not listed because of a shortage of donor organs. In recent cohorts, there is better outcome when ventricular assist devices (VADs) rather than extracorporeal membrane oxygenation are used as a 'bridge' to transplantation. Anesthesiologists working in centers where VADs are available may increasingly be asked to provide anesthesia to children with such devices in situ, including procedures outside the cardiac surgical operating room. The Berlin Heart EXCOR device is a VAD system with increasing popularity in pediatric practice and has system components available in sizes suitable even for neonates. Postimplantation considerations include hemodynamics, thromboembolic complications and their prevention by anticoagulation, antimicrobial therapy, and the rehabilitation and mobilization of recipients. VAD-specific emergencies must be recognized and managed appropriately by anesthesiologists looking after Berlin Heart recipients. These include malignant dysrhythmias, sudden loss of VAD output, air or clot embolism, and sudden cyanosis. Provision of anesthesia for patients with an in situ Berlin Heart requires attention to particular considerations in preoperative assessment, induction, maintenance, and postoperative care.
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