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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

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Updated: Jun 10, 2026

An Innovative Method for Exosome Quantification and Size Measurement
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Optical particle sizing: an introduction by the feature editors.

E D Hirleman, C F Bohren

    Applied Optics
    |August 19, 2010
    PubMed
    Summary

    This special issue presents 36 papers on optical particle sizing methods. These contributions stem from the Second International Congress on Optical Particle Sizing, advancing particle-size measurement techniques.

    Area of Science:

    • Optics and Photonics
    • Particle Science and Technology

    Background:

    • The Second International Congress on Optical Particle Sizing convened in Tempe, Arizona, March 1990.
    • This congress is part of a series of international meetings focused on optical particle-size measurement techniques, held every three years.

    Purpose of the Study:

    • To compile and disseminate cutting-edge research on optical particle sizing methods.
    • To document advancements presented at the Second International Congress on Optical Particle Sizing.

    Main Methods:

    • Collection of 36 peer-reviewed papers presented at the congress.
    • Focus on diverse optical techniques for determining particle size.

    Main Results:

    • A comprehensive collection of 36 papers detailing advancements in optical particle sizing.

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  • Showcasing a broad spectrum of methodologies and applications in the field.

    • Conclusions:

    • The congress successfully fostered international collaboration and knowledge exchange in optical particle sizing.
    • The series of congresses is crucial for the progression of particle-size measurement technologies.