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The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
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Related Experiment Video

Updated: Jun 10, 2026

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue
10:17

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Published on: June 18, 2014

Analytical inversion for laser diffraction spectrometry giving improved resolution and accuracy in size distribution.

J C Knight, D Ball, G N Robertson

    Applied Optics
    |August 19, 2010
    PubMed
    Summary

    This study presents a new Chin-Shifrin integral transform inversion method for determining particle-size distribution from forward-scattering data without needing data derivatives. The technique minimizes noise for accurate particle analysis.

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    Last Updated: Jun 10, 2026

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    Characterization of Nanocrystal Size Distribution using Raman Spectroscopy with a Multi-particle Phonon Confinement Model
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    Characterization of Nanocrystal Size Distribution using Raman Spectroscopy with a Multi-particle Phonon Confinement Model

    Published on: August 22, 2015

    Area of Science:

    • Physics
    • Materials Science
    • Analytical Chemistry

    Background:

    • Particle-size distribution analysis is crucial in various scientific fields.
    • Forward-scattering techniques are commonly used for particle characterization.
    • Existing inversion methods often require derivative data, limiting their applicability.

    Purpose of the Study:

    • To develop a novel Chin-Shifrin integral transform inversion method.
    • To enable particle-size distribution calculation without requiring data derivatives.
    • To improve the robustness and applicability of forward-scattering analysis.

    Main Methods:

    • Formulation of the Chin-Shifrin integral transform inversion.
    • Development of equations suitable for photodiode array detectors.
    • Implementation of controlled integration ranges and signal apodization.
    • Noise reduction strategies for improved inversion accuracy.

    Main Results:

    • Successful inversion of particle-size distribution from forward-scattering patterns.
    • Demonstration of a method independent of derivative data.
    • Achieved acceptable noise levels through optimized inversion parameters.
    • Presented sample analyses validating the method's effectiveness.

    Conclusions:

    • The developed Chin-Shifrin inversion method offers a robust alternative for particle-size distribution analysis.
    • The technique is practical for use with standard photodiode array instruments.
    • Noise reduction strategies enhance the reliability of the particle-size analysis.