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Proteomics in nutrition: status quo and outlook for biomarkers and bioactives

Martin Kussmann1, Alexandre Panchaud, Michael Affolter

  • 1Functional Genomics Group, Department of BioAnalytical Sciences, Nestlé Research Center, Lausanne, Switzerland. martin.kussmann@rdls.nestle.com

Journal of Proteome Research
|August 20, 2010
PubMed

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Bioavailability refers to the proportion of an unaltered drug that, after administration, enters the systemic circulation and can be distributed to the desired action site. Factors such as gastrointestinal (GI) absorption and liver biotransformation influence the bioavailability of a drug when it is administered orally. When a drug is administered intravenously, it enters the systemic circulation directly; by definition, its bioavailability is assumed to be 100%. The bioavailability of an...
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