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Updated: Jun 10, 2026

Ultrasound-based Pulse Wave Velocity Evaluation in Mice
Published on: February 14, 2017
New method for expressing F-wave data as conduction velocity
1Department of Physical Medicine and Rehabilitation, Tufts, New England Medical Center, Boston, Massachusetts, U.S.A.; Department of Neurology, Boston University, Boston, Massachusetts, U.S.A.; Boston VA Medical Center, Boston, Massachusetts, U.S.A.
Abstract:
A method for expressing F-wave data as a conduction velocity (normalized F-wave conduction velocity, NFCV) is described for the median, ulnar, peroneal, and posterior tibial nerves. Surface measurements routinely performed for calculation of motor conduction velocity (MCV) are used together with F-wave latency and a compensation factor (CF) to calculate a "velocity" easily comparable (normalized) to the MCV. Significant correlations between segmental "limb lengths" and whole 'extremity lengths" are shown. High correlations between NFCV and MCV are shown in a normal population, implying that NFCV is a valid descriptor of nerve conduction although it is not the true F-wave conduction velocity. The NFCV is shown to be more sensitive to age than F-wave latency or MCV, implying that NFCV potentially may be used as a sensitive indicator of motor nerve pathology.
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