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Updated: Jun 10, 2026
Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake
Published on: September 21, 2017
Molecular imaging of the dopamine transporter
Andrea Varrone1, Christer Halldin
1Centre for Psychiatry Research, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden. andrea.varrone@ki.se
Abstract:
The dopamine transporter (DAT) is a transmembrane protein responsible for reuptake of dopamine from the synaptic cleft and termination of dopaminergic transmission. Several radioligands are available for DAT imaging with SPECT and PET. This review summarizes the main SPECT and PET radioligands and the main applications of DAT imaging in neuropsychiatric disorders.
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