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Updated: Jun 10, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Stenotrophomonas maltophilia endocarditis of prosthetic mitral valve
Takuji Katayama1, Yoshio Tsuruya, Susumu Ishikawa
1Division of Cardiology, Tokyo Kita Social Insurance Hospital, Tokyo, Japan. taku-iku-mm@fa2.so-net.ne.jp
Abstract:
We present a 78-year-old woman with prosthetic valve endocarditis due to Stenotrophomonas maltophilia (S. maltophilia) 3 years after mitral valve replacement. Administration of sulfamethoxazole-trimethoprim was effective; however, it was discontinued because of side effects, which led to failure of antibiotic therapy. Complications of multiple cerebral infarction and paravalvular abscess developed. Although the prosthetic valve was removed 50 days after admission, she died 4 months after surgery. S. maltophilia has been increasingly being considered as a serious nosocomial pathogen. S. maltophilia endocarditis is rare; however, it should be recognized as a possible life-threatening disease in patients with prosthetic valve.
Insights
Stenotrophomonas maltophilia endocarditis is a rare but serious condition in patients with prosthetic valves. This case highlights the challenges of antibiotic treatment and potential fatal outcomes.
Area of Science:
- Infectious Diseases
- Cardiology
- Critical Care Medicine
Background:
- Prosthetic valve endocarditis (PVE) poses significant risks.
- Stenotrophomonas maltophilia (S. maltophilia) is an emerging nosocomial pathogen.
- PVE caused by S. maltophilia is exceptionally rare.
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