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Updated: Jun 10, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

Using targeted spirometry to reduce non-diagnosed chronic obstructive pulmonary disease.

Lea Schirnhofer¹, Bernd Lamprecht, Natalie Firlei

¹Department of Pulmonary Medicine, Paracelsus Medical University Hospital, Salzburg, Austria. l.schirnhofer @ salk.at

Respiration; International Review of Thoracic Diseases

|August 20, 2010

Summary

Undiagnosed chronic obstructive pulmonary disease (COPD) is common. Targeted spirometry in individuals with respiratory symptoms and risk factors can halve the rate of undiagnosed irreversible airway obstruction (AO).

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Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

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Area of Science:

Pulmonary Medicine
Epidemiology

Background:

Chronic obstructive pulmonary disease (COPD) prevalence is rising globally, contributing significantly to morbidity and mortality.
A substantial number of COPD cases remain undiagnosed, hindering timely intervention and management.

Purpose of the Study:

To determine the prevalence of undiagnosed irreversible airway obstruction (AO) in a population sample.
To characterize individuals with undiagnosed AO.
To assess the impact of targeted spirometry on reducing COPD underdiagnosis.

Main Methods:

1,258 adults aged 40+ completed questionnaires and pre- and post-bronchodilator spirometry.
Irreversible AO was defined by post-bronchodilator FEV1/FVC ratio below the lower limit of normal.
Targeted spirometry eligibility was based on respiratory symptoms and risk factors (smoking, occupational exposure) without a prior COPD diagnosis.

Main Results:

85.9% of participants with irreversible AO had no prior COPD diagnosis.
Undiagnosed AO was less common in severe cases and inversely related to age and prior respiratory conditions.
Targeted spirometry identified irreversible AO in 25.1% of eligible individuals, potentially reducing overall underdiagnosis by 50.3%.

Conclusions:

Spirometry screening in symptomatic individuals with risk factors can effectively halve the rate of undiagnosed irreversible AO.
Identifying and addressing undiagnosed AO is crucial for reducing the global burden of COPD.