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Updated: Jun 10, 2026
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
Liver transplantation in swine without venovenous bypass
M Heuer1, R Reinhardt, G Kneiseler
1Department of General, Visceral and Transplantation Surgery, University Hospital of Essen, Essen, Germany.
Introduction:
A model of orthotopic liver transplantation in swine was developed to investigate an advanced reperfusion approach. Thereby, we consciously disclaim otherwise commonly practiced venovenous bypass during the recipient operation.
Material And Methods:
Ten liver transplantations were performed according to the described technique without using venovenous bypass. In each swine the observation period was 48 h.
Results:
All transplantations were carried out after a median cold ischemic time of 307.5 min (295-340); the median warm ischemic time in these cases was 25 min (20-32). Eight of 10 swine survived 48 h after the operation.
Conclusion:
Orthotopic liver transplantations in the recipient swine are feasible even without using venovenous bypass.
