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Related Concept Videos

Colloidal precipitates01:09

Colloidal precipitates

The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
Colloids03:22

Colloids

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
Colloids and Suspensions01:17

Colloids and Suspensions

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...
The Colloidal State01:29

The Colloidal State

The formation of a colloidal system is exemplified by an aqueous solution containing Cl− ions is introduced to another containing Ag+ ions, resulting in the precipitation of solid AgCl as extremely tiny crystals. Instead of settling out as a filterable precipitate, these crystals remain suspended in the liquid, showcasing a colloidal system.A colloidal system involves colloidal particles within the approximate range of 1 to 1000 nm in at least one dimension, dispersed in a medium called the...
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Coagulation01:06

Coagulation

Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...

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Updated: Jun 10, 2026

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY
10:28

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Published on: June 30, 2016

Optical path clearing and enhanced transmission through colloidal suspensions.

J Baumgartl1, T Cizmár, M Mazilu

  • 1School of Physics and Astronomy, University of St. Andrews, North Haugh, St Andrews KY16 9SS, UK. jb211@st-andrews.ac.uk

Optics Express
|August 20, 2010
PubMed
Summary
This summary is machine-generated.

Advanced laser fields create clear paths in turbid media through Optical Path Clearing (OPC). This method evacuates particles using tailored laser forces, paving the way for efficient particle manipulation in dynamic environments.

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Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY
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Published on: June 30, 2016

Rapid Optical Clearing for Semi-High-Throughput Analysis of Tumor Spheroids
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Area of Science:

  • Physics
  • Optics
  • Materials Science

Background:

  • Dynamic turbid media present challenges for light propagation and manipulation.
  • Controlling particle distribution in suspensions is crucial for various applications.

Purpose of the Study:

  • To introduce and demonstrate Optical Path Clearing (OPC) in dynamic turbid media.
  • To investigate methods for efficient particle evacuation from a defined volume.

Main Methods:

  • Utilizing advanced laser fields with tailored spatial profiles.
  • Employing gradient and scattering forces for particle manipulation.
  • Conducting analytical modeling and proof-of-principle experiments in colloidal suspensions.

Main Results:

  • Successfully cleared paths in dense bulk colloidal suspensions.
  • Demonstrated particle evacuation using laser-induced forces.
  • Identified key parameters for effective path clearing.

Conclusions:

  • Optical Path Clearing (OPC) is a viable technique for dynamic turbid media.
  • Multiple-step clearing with dynamic laser fields (Airy or inverted axicon beams) promises high performance and efficiency.