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Related Experiment Video

Updated: Jun 10, 2026

Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

Metal microneedle fabrication using twisted light with spin.

Takashige Omatsu1, Keisuke Chujo, Katsuhiko Miyamoto

  • 1Graduate School of Advanced Integration Science, Chiba University, Chiba 263-8522, Japan. omatsu@faculty.chiba-u.jp

Optics Express
|August 20, 2010
PubMed
Summary

Researchers achieved novel microneedle fabrication on metal using laser ablation with twisted light. This technique produced high-aspect-ratio needles and arrays for potential microdevice applications.

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Area of Science:

  • Materials Science
  • Optics
  • Nanotechnology

Background:

  • Microneedle technology is crucial for minimally invasive drug delivery and diagnostics.
  • Existing fabrication methods often face limitations in precision and scalability.
  • Laser-based techniques offer potential for high-resolution material processing.

Purpose of the Study:

  • To demonstrate, for the first time, microneedle fabrication on metal surfaces using laser ablation with twisted light.
  • To characterize the dimensions and uniformity of the fabricated microneedles and arrays.
  • To explore the potential of this novel technique for microfabrication.

Main Methods:

  • Utilized laser ablation with twisted light possessing spin.
  • Fabricated individual microneedles on a metal surface.

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Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole
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Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Published on: December 5, 2025

Related Experiment Videos

Last Updated: Jun 10, 2026

Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole
06:25

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Published on: December 5, 2025

  • Created a two-dimensional microneedle array (5 x 6).
  • Characterized needle height, tip diameter, and uniformity using microscopy.

    • Main Results:

    • Successfully fabricated microneedles with heights of at least 10 micrometers and tip diameters below 0.3 micrometers.
    • Demonstrated the fabrication of a uniform 5 x 6 microneedle array.
    • Achieved average needle lengths of approximately 10 micrometers and tip diameters of 0.5 micrometers for the array.
    • Confirmed uniform shape and consistent dimensions across the array.

    Conclusions:

    • Laser ablation using twisted light is a viable and novel method for high-precision microneedle fabrication on metal.
    • The demonstrated technique allows for the creation of high-aspect-ratio microneedles and uniform arrays.
    • This advancement opens new possibilities for microdevices and applications requiring precise microneedle structures.