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Related Experiment Video

Updated: Jun 10, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood
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Published on: April 28, 2016

Ghrelin and functional dyspepsia.

Takashi Akamizu1, Hiroshi Iwakura, Hiroyuki Ariyasu

  • 1Ghrelin Research Project, Translational Research Center, Kyoto University Hospital, Kyoto University School of Medicine, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.

International Journal of Peptides
|August 20, 2010
PubMed
Summary
This summary is machine-generated.

Functional dyspepsia (FD) involves altered stomach function and ghrelin levels, impacting digestion and appetite. Ghrelin therapy shows promise for treating FD symptoms and weight loss in affected patients.

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Last Updated: Jun 10, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood
11:36

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

Published on: April 28, 2016

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
06:40

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management

Published on: June 29, 2019

Area of Science:

  • Gastroenterology
  • Neurogastroenterology
  • Endocrinology

Background:

  • Functional dyspepsia (FD) affects many patients without a clear cause.
  • Brain-gut communication via neural and endocrine systems is crucial for gut function.
  • Ghrelin, a stomach peptide, influences gastric motility, emptying, and secretion.

Purpose of the Study:

  • To investigate the potential role of ghrelin in the pathophysiology of FD.
  • To explore the relationship between ghrelin levels and FD symptoms.
  • To assess ghrelin's potential as a therapeutic agent for FD.

Main Methods:

  • Analysis of plasma ghrelin levels in FD patients.
  • Correlation of ghrelin levels with FD symptom scores.
  • Review of ghrelin's known effects on gastric function and feeding behavior.

Main Results:

  • Plasma ghrelin levels are altered in FD patients.
  • Ghrelin levels correlate with the severity of FD symptoms.
  • Some FD patients experience anorexia and weight loss.

Conclusions:

  • Ghrelin may play a role in the functional abnormalities observed in FD.
  • Altered ghrelin production or signaling could contribute to FD pathophysiology.
  • Ghrelin therapy presents a potential novel treatment strategy for FD, particularly for those with anorexia and weight loss.