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Updated: Jun 10, 2026

Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue
Published on: January 19, 2019
Ictal bigeminy
1Institute of Neurology and Neurosurgery, St. Barnabas, Livingston, New Jersey, USA. pwiddesswalsh@sbhcs.com
Abstract:
Seizures can influence cardiac autonomic function and cause abnormalities in the electrocardiogram (EKG). A case of stereotypical bigeminy during left temporal lobe seizures recorded in the epilepsy monitoring unit is presented. The mechanism is likely due to spread of the ictal discharge to primary visceromotor regions in the left insula (Island of Reil). This case illustrates the potential influence of ictal brain activity on cardiac electrophysiology.
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Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

