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Induced domain formation in endocytic invagination, lipid sorting, and scission
Ludger Johannes1, Satyajit Mayor
1Institut Curie, Centre de Recherche, Traffic, Signaling, and Delivery Laboratory, 75248 Paris Cedex 05, France. mayor@ncbs.res.in
Abstract:
Lipid segregation occurs in biological membranes, but how this plays into cellular processes like endocytosis has been unclear. Here, we discuss how the active or passive induction of lipid-protein domain formation in membranes can alter membrane mechanics and thus affect processes such as the generation of curvature, the scission of buds and tubules, and lipid sorting.
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