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Updated: Jun 10, 2026

An Orthotopic Resectional Mouse Model of Pancreatic Cancer
Published on: September 24, 2020
[Distal pancreas resection for metastasis of clear cell renal cancer]
Károly Gábor Szabó1, Zsolt Szentkereszty, László András Tóth
1Debreceni Egyetem Orvos- és Egészségtudományi Centrum Sebészeti Intézet 4032 Debrecen Móricz Zsigmond krt. 22.
Background:
Distant spread from renal cell carcinoma is commonly found in the liver and lung. Metastatic involvement of any other gastro-intestinal organ (duodenum, other kidney, adrenal gland) is unexpected. However, clear cell renal carcinoma is known to cause pancreatic metastasis.
Methods:
The authors present the case of a successfully operated 82- year-old man, who was operated for a metastatic tumor in his pancreas. 8 years prior to his current hospitalization, a left sided nephrectomy was performed for renal cell carcinoma. The CT scan revealed a tumor localised in the tail of the pancreas. Distal pancreas resection was performed with splenectomy. Histology revealed clear cell renal carcinoma metastasis.
Conclusions:
pancreatic tumors are mostly primaries. Renal cell carcinoma generally gives hepatic and pulmonary metastases. However, clear cell renal carcinoma is known to give pancreatic metastasis, too.

