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Related Experiment Video

Updated: Jun 10, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

Optical coherence tomography for corneal diseases.

Naoyuki Maeda¹

¹Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan. nmaeda@ophthal.med.osaka-u.ac.jp

Eye & Contact Lens

|August 21, 2010

Summary

Anterior segment optical coherence tomography (OCT) provides detailed corneal imaging for surgical planning and disease diagnosis. Advanced OCT techniques offer 3D, tissue, and cell imaging for enhanced ophthalmic analysis.

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Area of Science:

Ophthalmology
Biomedical Imaging
Corneal Science

Background:

Anterior segment optical coherence tomography (OCT) is a key tool in ophthalmology.
It is used for analyzing corneal thickness, stromal interface, graft-host junctions, anterior chamber dimensions, and corneal lesions.

Purpose of the Study:

This review highlights the capabilities of advanced OCT technology in ophthalmology.
It focuses on three-dimensional imaging, tissue imaging, cell imaging, and topographic analysis.

Main Methods:

The review discusses examples of spectral-domain OCT (840-nm) for tissue imaging.
It also covers full-field OCT for cell imaging and swept-source OCT (1,310-nm) for corneal topographic analysis.

Main Results:

Advanced OCT enables detailed visualization of corneal structures and pathologies.
Specific OCT technologies offer distinct advantages for different ophthalmic applications.

Conclusions:

OCT technology has significantly advanced ophthalmic diagnostics and surgical assessment.
Future applications of OCT in corneal imaging are promising for improved patient outcomes.