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Updated: Jun 10, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
Optical coherence tomography for corneal diseases
1Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan. nmaeda@ophthal.med.osaka-u.ac.jp
Abstract:
Anterior segment optical coherence tomography (OCT) is currently used for investigating the distribution of the corneal thickness, shape of the stromal interface after lamellar corneal surgery, association between host and corneal graft in keratoplasty, dimension of the anterior chamber, and lesions of the corneal diseases. In addition, the advances of OCT technology has enabled three-dimensional imaging, tissue imaging, cell imaging, and topographic analysis. In this review, examples of tissue imaging with 840-nm spectral-domain OCT, cell imaging with full-field OCT, and corneal topographic analysis with 1,310-nm swept-source OCT were introduced.
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