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[Spinal anesthesia with pethidine as the sole agent]
1Department of Anesthesiology, Daiichi Hospital, Nippon Medical School, Tokyo.
Masui. the Japanese Journal of Anesthesiology
|March 1, 1991
Summary
Intrathecal pethidine provided prolonged postoperative analgesia for perineal surgery. Higher doses (0.7 mg/kg) achieved better sensory blockade than lower doses (0.5 mg/kg).
Area of Science:
- Anesthesiology
- Pain Management
- Surgical Procedures
Background:
- Intrathecal pethidine is utilized for regional anesthesia.
- Its efficacy and optimal dosage for perineal surgery require further evaluation.
Purpose of the Study:
- To compare the anesthetic effects of two different intrathecal pethidine doses.
- To evaluate the safety and efficacy of intrathecal pethidine for perineal surgery.
Main Methods:
- Twenty-two patients received either 0.5 mg/kg (Group 1) or 0.7 mg/kg (Group 2) of intrathecal pethidine.
- Subarachnoid puncture at L4/5 or L5/S, followed by 5 minutes in a sitting position.
- Anesthetic effects, sensory blockade levels, and motor blockade were assessed.
Main Results:
- The 0.7 mg/kg dose resulted in a higher average segmental level of analgesia (L2) compared to 0.5 mg/kg (S1).
- All patients experienced motor blockade of the anal sphincter.
- Hemodynamic stability and absence of respiratory depression were observed; prolonged postoperative analgesia was achieved.
Conclusions:
- Intrathecal pethidine is effective for perineal surgery, offering prolonged postoperative pain relief.
- A dose of 0.7 mg/kg appears more effective for achieving adequate sensory blockade.
- Minor side effects included itching and nausea; arrhythmias were infrequent.