Related Experiment Video
Updated: Jun 10, 2026
10:34
An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse
Published on: August 7, 2013
Enteric nervous system in the small intestine: pathophysiology and clinical implications
Behtash Ghazi Nezami1, Shanthi Srinivasan
1Division of Digestive Diseases, Emory University School of Medicine and VAMC, Whitehead Research Building, Suite 246, 615 Michael St., Atlanta, GA 30307, USA. bg.nezami@emory.edu
Current Gastroenterology Reports
|August 21, 2010
Summary
The small intestine
Area of Science:
- Gastroenterology and Neuroscience
Background:
- The digestive system possesses a local nervous system, the enteric nervous system (ENS).
- The small intestine's ENS has unique characteristics influencing motility, secretion, digestion, and inflammation.
Purpose of the Study:
- To review recent advancements in understanding small intestinal ENS function.
- To explore the development of novel therapies targeting the small intestinal ENS.
Main Methods:
- Literature review of recent research on enteric nervous system signaling pathways.
- Analysis of studies focusing on small intestinal ENS regulation of physiological processes.
Main Results:
- Significant progress has been made in elucidating ENS signaling pathways.
- New insights into the regulation of immune response, nutrient detection, and barrier function by the ENS.
Conclusions:
- Recent research has deepened our understanding of small intestinal ENS.
- These insights are paving the way for innovative therapeutic strategies.
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