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Narrow band UVB: is it effective and safe for paediatric psoriasis and atopic dermatitis?

M Pavlovsky1, S Baum, D Shpiro

  • 1Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. masha_krup@yahoo.com

Journal of the European Academy of Dermatology and Venereology : JEADV
|August 24, 2010
PubMed

Insights

Narrow-band UVB (NB-UVB) phototherapy shows promise for treating pediatric psoriasis and atopic dermatitis (AD), with good tolerability. Longer follow-up is needed to confirm long-term safety and efficacy in children.

Area of Science:

  • Pediatric Dermatology
  • Phototherapy Research
  • Dermatologic Treatments

Background:

  • Phototherapy is established for adult skin conditions but limited in children due to cancer concerns.
  • Few trials exist on pediatric phototherapy efficacy and safety.
  • Concerns about long-term carcinogenic potential restrict its use in pediatric populations.

Purpose of the Study:

  • To evaluate the efficacy and safety of narrow-band UVB (NB-UVB) phototherapy.
  • To assess treatment outcomes for children diagnosed with atopic dermatitis (AD) and psoriasis.

Main Methods:

  • Retrospective review of 129 pediatric patients with psoriasis and AD.
  • Treatment administered between 1998 and 2006 using NB-UVB.
  • Analysis of treatment outcomes, including disease clearance and adverse events.

Main Results:

  • Clearance achieved in 50% of pediatric psoriasis patients.
  • Clearance achieved in 25% of pediatric atopic dermatitis patients.
  • NB-UVB was well-tolerated; one suspected case of melanoma in situ was noted.

Conclusions:

  • NB-UVB is a potential therapeutic option for pediatric psoriasis and AD.
  • Annual dermatologic observation is recommended for children undergoing phototherapy.
  • Extended follow-up studies are essential to ascertain the true carcinogenic risk of UV therapy in children.
Abstract

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