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Incretin-based therapy in chronic kidney disease
Nicole R Pinelli1, Carol L Moore, Sarah Tomasello
1Department of Pharmacy Practice, Wayne State University, Detroit, MI 48201-2427, USA. nickipinelli@wayne.edu
Advances in Chronic Kidney Disease
|August 24, 2010
Summary
Type 2 diabetes with kidney disease presents treatment challenges. Incretin-based therapies offer a new option for managing blood sugar in these patients.
Area of Science:
- Nephrology
- Endocrinology
- Pharmacology
Background:
- Type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) co-occurrence is a growing public health issue.
- Glycemic control is difficult in T2DM patients with CKD due to medication limitations.
Purpose of the Study:
- To review the efficacy and safety of incretin-based therapies for T2DM patients with CKD.
Main Methods:
- Literature review of studies on incretin-based therapies in T2DM and CKD patients.
Main Results:
- Incretin-based therapies represent a novel approach to hyperglycemia management.
- Evidence for the use of these agents in CKD populations is emerging.
Conclusions:
- Incretin-based therapies show promise for T2DM patients with CKD.
- Further research is needed to fully establish their role in this population.
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