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Alternative splicing of genes during neuronal differentiation of NT2 pluripotential human embryonal carcinoma cells

Ai Wakamatsu1, Jun-ichi Imai, Shinya Watanabe

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

FEBS Letters
|August 24, 2010
PubMed

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Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
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