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[Efficiency and safety of recombinant activated factor VII in a case of severe postpartum hemorrhage]

A Geiger1, O Collange, J Samin

  • 1Service d'anesthésie-réanimation, hôpital de Hautepierre, 1 avenue Molière, Strasbourg cedex, France.

Annales Francaises D'Anesthesie Et De Reanimation
|August 24, 2010
PubMed

We report the case of a severe postpartum hemorrhage (PPH) that was successfully treated with two administrations of recombinant activated factor VII (rFVIIa). Two major thromboembolic events (TEE) occurred shortly afterwards: the first was an acute lower limb ischemia at H3, the second was a cardiac arrest complicating a massive pulmonary embolism on day 5. Fortunately, both events had a favorable outcome. This case report allows us to discuss the role of rFVIIa during severe PPH and its potential responsibility in these two major TEE.

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