Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 10, 2026

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
12:20

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

Aptamers based electrochemical biosensor for protein detection using carbon nanotubes platforms.

Pinar Kara1, Alfredo de la Escosura-Muñiz, Marisa Maltez-da Costa

  • 1Nanobioelectronics & Biosensors Group, Institut Català de Nanotecnologia, CIN2 (CSIC), Campus UAB, Barcelona, Spain.

Biosensors & Bioelectronics
|August 24, 2010
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Fully-printed microneedles meet plants: a pathway towards easy-to-use NFC monitoring of total ionic conductivity in precision agriculture" [Biosens. Bioelectron. 306 (2026) 118667].

Biosensors & bioelectronics·2026
Same author

Electrochemical aptasensing reveals serum myelin alterations in diabetic neuropathy.

Analytical biochemistry·2026
Same author

A paper-based fluorescent biosensing platform for miRNA detection with dual high-throughput and smartphone readout.

Biosensors & bioelectronics·2026
Same author

Lipoprotein(a) cascade screening in coronary artery disease.

Atherosclerosis·2026
Same author

Fully-printed microneedles meet plants: a pathway towards easy-to-use NFC monitoring of total ionic conductivity in precision agriculture.

Biosensors & bioelectronics·2026
Same author

Laser-Assisted In Situ Fabrication of rGO/Bi<sub>2</sub>O<sub>3</sub> Nanocomposites for Heavy Metal Sensing.

Small (Weinheim an der Bergstrasse, Germany)·2026

This study presents a novel label-free electrochemical biosensor for detecting thrombin protein. Using aptamer-modified carbon nanotubes, it achieves sensitive protein detection via electrochemical impedance spectroscopy (EIS).

Area of Science:

  • Bioelectronics
  • Biosensor Technology
  • Electrochemistry

Background:

  • Label-free detection methods are crucial for sensitive protein analysis.
  • Electrochemical impedance spectroscopy (EIS) offers a label-free transduction mechanism.
  • Aptamers provide high specificity for target biomolecule recognition.

Purpose of the Study:

  • To develop a novel label-free bioelectronic sensor for aptamer-thrombin interaction.
  • To utilize multiwalled carbon nanotubes (MWCNTs) for enhanced sensor performance.
  • To establish a sensitive electrochemical detection method for thrombin.

Main Methods:

  • Screen-printed carbon electrotransducers (SPCEs) were modified with MWCNTs.
  • An amino-linked aptamer sequence was immobilized on the MWCNT-modified SPCEs.

More Related Videos

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes
09:28

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Published on: January 10, 2017

Gold Nanoparticle Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection
07:34

Gold Nanoparticle Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection

Published on: May 13, 2019

Related Experiment Videos

Last Updated: Jun 10, 2026

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
12:20

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes
09:28

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Published on: January 10, 2017

Gold Nanoparticle Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection
07:34

Gold Nanoparticle Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection

Published on: May 13, 2019

  • Electrochemical impedance spectroscopy (EIS) was employed to monitor thrombin binding by measuring charge transfer resistance (Rct).

    • Main Results:

    • MWCNT modification improved SPCE characteristics for bio-detection.
    • The aptamer-thrombin interaction was successfully monitored using EIS.
    • A sensitive detection limit of 105 pM for thrombin was achieved.

    Conclusions:

    • A label-free, MWCNT-enhanced electrochemical biosensor for thrombin detection was successfully developed.
    • The sensor demonstrates high sensitivity and offers an alternative for protein detection.
    • This approach holds promise for future applications in protein analysis and diagnostics.