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Discordant expression of miR-103/7 and pantothenate kinase host genes in mouse

Brenda J Polster1, Shawn K Westaway, Thuy M Nguyen

  • 1Molecular and Medical Genetics, Oregon Health & Science University, Portland OR, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA. polsterb@ohsu.edu

Molecular Genetics and Metabolism
|August 24, 2010
PubMed

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...