Related Experiment Video
Updated: Jun 10, 2026

10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Migraine accompagnée after transseptal puncture
L Jordaens1, P Janse, T Szili-Torok
1Department of Cardiology, Thoraxcentre, Erasmus MC, Rotterdam, the Netherlands.
Summary
Transseptal puncture during atrial fibrillation ablation may cause new-onset migraine or worsen existing migraines in some patients. Most symptoms resolved within three months post-procedure.
Area of Science:
- Cardiology
- Neurology
- Medical Procedures
Background:
- Transseptal puncture is a key step in atrial fibrillation ablation.
- Migraine as a complication of this procedure has not been previously documented.
- Initial observations suggested a link between transseptal puncture and new or exacerbated migraines.
Purpose of the Study:
- To investigate the incidence of new-onset migraine and migraine exacerbation following transseptal puncture for atrial fibrillation ablation.
- To assess the temporal relationship between the procedure and migraine symptoms.
Main Methods:
- Prospective study evaluating patients undergoing pulmonary vein isolation using transseptal puncture.
- Utilized a 15 Fr sheath for transseptal access.
- Patients completed questionnaires at three months post-intervention to report headache and migraine symptoms.
Main Results:
- 8% of procedures were associated with new-onset migraine with ocular symptoms within three months.
- 7% of patients reported exacerbation of pre-existing migraine.
- Higher incidence of complaints observed in redo procedures.
- Most migraine symptoms resolved by the three-month follow-up.
Conclusions:
- Transseptal puncture for atrial fibrillation ablation can be associated with new or worsened migraine symptoms.
- These symptoms appear to be transient, with most resolving by three months.
- This finding has implications for patient follow-up protocols after ablation procedures.
Related Concept Videos
Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Epistaxis
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
