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Updated: Jun 10, 2026
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Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
Auditory evoked potentials and multiple sclerosis.
Carla Gentile Matas1, Sandro Luiz de Andrade Matas, Caroline Rondina Salzano de Oliveira
1Speech Pathology and Audiology Course, FMUSP. cgmatas@usp.br
Arquivos De Neuro-Psiquiatria
|August 24, 2010
Summary
Multiple sclerosis (MS) affects the auditory pathway, causing abnormal auditory evoked potentials. This indicates central auditory nervous system dysfunction in individuals with MS.
Area of Science:
- Neuroscience
- Audiology
- Neurology
Background:
- Multiple sclerosis (MS) is an inflammatory demyelinating disease impacting the central nervous system.
- Damage to the auditory pathway in MS can significantly affect its integrity.
- Investigating the auditory pathway from brainstem to cortex in MS patients is crucial.
Purpose of the Study:
- To characterize auditory evoked potentials in adults with relapsing-remitting MS.
- To identify auditory pathway abnormalities in MS patients.
Main Methods:
- The study included 25 adults with MS and 25 healthy controls, aged 25-55.
- Participants underwent comprehensive audiological and electrophysiological evaluations.
- Auditory evoked potentials were assessed.
Main Results:
- Significant differences were found in auditory brainstem response between MS patients and controls.
- Latency of Na and P300 waves showed statistically significant differences.
- Abnormalities in auditory evoked potentials were observed in the MS group.
Conclusions:
- Individuals with MS exhibit auditory evoked potential abnormalities.
- These findings suggest dysfunction in various regions of the central auditory nervous system in MS.
- Auditory evoked potentials are valuable indicators of neurological changes in MS.
