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Related Concept Videos

Enzyme-linked Receptors01:00

Enzyme-linked Receptors

Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
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G-Protein Gated Ion Channels

GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
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Mechanically-gated Ion Channels01:12

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Related Experiment Video

Updated: Jun 10, 2026

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy
08:27

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy

Published on: January 7, 2019

TRP channels in human prostate.

Carl Van Haute1, Dirk De Ridder, Bernd Nilius

  • 1Department of Molecular Cell Biology, Laboratory of Ion Channel Research, Campus Gasthuisberg, KULeuven, Belgium. carl.vanhaute@med.kuleuven.be

Thescientificworldjournal
|August 24, 2010
PubMed
Summary
This summary is machine-generated.

This review explores human prostate morphology and function, focusing on transient receptor potential (TRP) channels. It discusses their role in normal prostate physiology, prostate cancer, and other diseases.

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Controllable Ion Channel Expression through Inducible Transient Transfection
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Controllable Ion Channel Expression through Inducible Transient Transfection

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Related Experiment Videos

Last Updated: Jun 10, 2026

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy
08:27

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy

Published on: January 7, 2019

Yeast Luminometric and Xenopus Oocyte Electrophysiological Examinations of the Molecular Mechanosensitivity of TRPV4
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Controllable Ion Channel Expression through Inducible Transient Transfection
10:00

Controllable Ion Channel Expression through Inducible Transient Transfection

Published on: February 17, 2017

Area of Science:

  • Urology
  • Molecular Biology
  • Cell Physiology

Background:

  • The human prostate's complex morphology and function are crucial for reproductive health.
  • Transient receptor potential (TRP) channels are implicated in various cellular processes.
  • Understanding TRP channel roles in the prostate is vital for addressing disease.

Purpose of the Study:

  • To review current knowledge on TRP channel expression in the human prostate.
  • To elucidate the putative role of TRP channels in prostate physiology and carcinogenesis.
  • To discuss controversial data on TRP channels in prostate function and disease.

Main Methods:

  • Literature review of studies on human prostate morphology and TRP channels.
  • Analysis of existing data on TRP channel expression patterns.
  • Synthesis of information regarding TRP channel involvement in prostate health and disease.

Main Results:

  • TRP channels are expressed in the human prostate, with varying patterns.
  • Evidence suggests TRP channels influence normal prostate function.
  • TRP channels are implicated in prostate carcinogenesis and other prostate pathologies.

Conclusions:

  • TRP channels represent key players in human prostate physiology and disease.
  • Further research is needed to resolve conflicting data on TRP channel expression and function.
  • Targeting TRP channels may offer therapeutic strategies for prostate conditions.