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Updated: Jun 10, 2026
03:05
Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
An indolent diffuse infiltrating gastric carcinoma.
V H Chong1, P U Telisinghe, S K Yapp
1Gastroenterology Unit, Department of Medicine, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan, BA 1710, Brunei Darussalam. chongvuih@yahoo.co.uk
Singapore Medical Journal
|August 24, 2010
Summary
This case study shows a gastric adenocarcinoma with a slow-growing, indolent course. Despite a six-year delay in treatment, the patient achieved a recurrence-free survival after surgery.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Gastric cancer is a leading cause of cancer mortality, frequently diagnosed at late stages.
- Delayed patient presentation often contributes to late diagnosis and treatment initiation.
Observation:
- A 48-year-old man was diagnosed with diffuse infiltrating gastric adenocarcinoma.
- The patient repeatedly declined surgical intervention over a six-year period despite similar diagnostic findings on repeat evaluations.
- Symptoms eventually prompted the patient to undergo surgery six years after initial diagnosis.
Findings:
- Histological analysis revealed a diffuse infiltrating stage T3 gastric tumor.
- The tumor exhibited a significant desmoplastic reaction.
- Lymph nodes were negative for metastasis (lymphadenopathies).
Implications:
- This case underscores that certain gastric cancers can exhibit an indolent clinical course.
- Curative treatment is achievable even after substantial delays in intervention.
- Highlights the importance of individualized treatment decisions in oncology.
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