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[Therapy-resistant otitis externa with additional tympanic membrane perforation: local therapy using N-chlorotaurine
M Lumassegger1, M Nagl, C Pototschnig
1Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde, Anichstrasse 35, 6020 Innsbruck, Osterreich.
Abstract:
Ear canal infections may not always be clinically distinguished between a bacterial otitis externa, an otomycosis or a mixed infection. In addition, tympanic membrane perforations are often not immediately apparent. The use of a broad-spectrum antiseptic agent without an inner ear toxic effect would therefore be beneficial. We report the case of a female patient suffering from intractable otitis externa with tympanic membrane perforation, who was successfully treated locally with a mixture of 1% NCT and 0.1% dexamethasone.
Insights
A novel antiseptic, 1% NCT (nanocrystalline silver), combined with dexamethasone, effectively treated a severe ear canal infection. This combination offers a safe and beneficial option for otitis externa, even with perforated eardrums.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Pharmacology
Context:
- Distinguishing between bacterial otitis externa, otomycosis, and mixed infections can be clinically challenging.
- Tympanic membrane perforations are not always immediately evident.
- A broad-spectrum antiseptic agent with minimal ototoxicity is needed.
Purpose:
- To evaluate the efficacy of a topical nanocrystalline silver (NCT) and dexamethasone mixture for intractable otitis externa with tympanic membrane perforation.
Summary:
- A female patient with persistent otitis externa and a perforated tympanic membrane was treated.
- Local application of a 1% NCT and 0.1% dexamethasone mixture resulted in successful treatment.
- The treatment demonstrated efficacy without apparent inner ear toxicity.
Impact:
- This case highlights the potential of topical NCT and dexamethasone as a safe and effective treatment for complex otitis externa.
- It provides a viable therapeutic option for ear canal infections where differentiation is difficult and tympanic membrane integrity is compromised.
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