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Related Experiment Video

Updated: Jun 10, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

Proteomic analysis in multiple myeloma research.

Jana Cumova1, Anna Potacova, Zbynek Zdrahal

  • 1University Research Centre - The Czech Myeloma Group (URC-CMG), Babak Research Institute, Faculty of Medicine, Masaryk University, Kamenice 5/A3, 625 00, Brno, Czech Republic. jazze@centrum.cz

Molecular Biotechnology
|August 24, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

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Multiple myeloma (MM) is a plasma cell malignancy. Proteomic analysis, particularly mass spectrometry, aids understanding MM's molecular mechanisms and treatment response prediction.

Area of Science:

  • Biochemistry
  • Oncology
  • Proteomics

Background:

  • Multiple myeloma (MM) is an incurable cancer of plasma cells (PCs).
  • Understanding MM's molecular drivers, microenvironment, and treatment response is crucial.
  • Genomic and proteomic analyses offer insights into MM pathogenesis.

Purpose of the Study:

  • To review common proteomic techniques for MM research.
  • To highlight applications of mass spectrometry in MM studies.
  • To provide a foundation for utilizing proteomics in multiple myeloma.

Main Methods:

  • Review of mass spectrometry-based proteomic techniques.
  • Discussion of separation methods coupled with mass spectrometry.
  • Examples of proteomic applications in multiple myeloma research.

Related Experiment Videos

Last Updated: Jun 10, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

Main Results:

  • Mass spectrometry is a key tool in proteomic analysis for MM.
  • Various proteomic techniques are applicable to studying MM.
  • Proteomics provides valuable data for understanding MM.

Conclusions:

  • Proteomic techniques, especially mass spectrometry, are essential for advancing multiple myeloma research.
  • These methods facilitate deeper understanding of MM molecular mechanisms.
  • Proteomics aids in predicting treatment responses in multiple myeloma.