Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fibronectin: structure, function and significance in wound healing.

H Brotchie1, D Wakefield

  • 1Department of Immunopathology, Prince Henry Hospital, Little Bay, NSW.

The Australasian Journal of Dermatology
|January 1, 1990
PubMed
Summary

Topical fibronectin shows therapeutic potential for chronic wounds. This protein aids healing by improving clotting, fighting infection, and promoting tissue regeneration for effective skin repair.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk factors associated with poorer experiences of end-of-life care and challenges in early bereavement: Results of a national online survey of people bereaved during the COVID-19 pandemic.

Palliative medicine·2022
Same author

The First Case Report of Schnitzler Syndrome Presenting with Eye Pain.

Ocular immunology and inflammation·2019
Same author

Outcome in a specialist referral clinic for mood disorders: a qualitative and quantitative review.

Acta neuropsychiatrica·2016
Same author

The natural history of acute Q fever: a prospective Australian cohort.

QJM : monthly journal of the Association of Physicians·2016
Same author

Tracing the fate of limbal epithelial progenitor cells in the murine cornea.

Stem cells (Dayton, Ohio)·2014
Same author

Human limbal epithelial progenitor cells express αvβ5-integrin and the interferon-inducible chemokine CXCL10/IP-10.

Stem cell research·2013

Area of Science:

  • Biomedical research
  • Wound healing science
  • Regenerative medicine

Background:

  • Chronic skin and corneal ulcers present significant clinical challenges.
  • Topical autologous fibronectin is emerging as a potential therapeutic agent.

Purpose of the Study:

  • To review the structural and functional properties of fibronectin.
  • To assess the therapeutic potential of fibronectin in wound healing based on recent research.

Main Methods:

  • Literature review of studies on fibronectin in wound healing.
  • Analysis of research published within the last five years.

Main Results:

  • Fibronectin plays a crucial role in multiple stages of wound repair.

Related Experiment Videos

  • It supports hemostasis, infection control, and debridement.
  • Fibronectin promotes re-epithelialization and granulation tissue formation.

    • Conclusions:

    • Fibronectin is a promising therapeutic adjunct for chronic wound management.
    • Understanding fibronectin's properties is key to optimizing its clinical application.
    • Further research supports its role in achieving adequate tensile strength for tissue repair.