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Related Experiment Video

Updated: Jun 9, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
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In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016

Extraskeletal Ewing's sarcoma presenting as a mediastinal mass.

Jane Halliday1, Sing Yang Soon, Hannah Monaghan

  • 1Department of Cardiothoracic Surgery, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom. jane.halliday@cantab.net

The Annals of Thoracic Surgery
|August 25, 2010
PubMed
Summary

Extraskeletal Ewing's sarcoma is a rare cancer. This study details a case of this rare tumor presenting as a mediastinal mass in a teenage boy.

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Area of Science:

  • Oncology
  • Pathology

Background:

  • Ewing's sarcoma family of tumors are rare malignant neoplasms.
  • Characterized by small blue, round-cell morphology, CD99, C-Kit, Bcl2 expression, and t(11:22) translocation.

Observation:

  • Extraskeletal Ewing's sarcoma typically affects soft tissues of the trunk or extremities.
  • A rare presentation of extraskeletal Ewing's sarcoma as a mediastinal mass was observed.

Findings:

  • The case involved a 16-year-old boy with a mediastinal mass.
  • Diagnostic features consistent with extraskeletal Ewing's sarcoma were identified.

Implications:

  • Highlights the diverse presentations of extraskeletal Ewing's sarcoma.
  • Emphasizes the importance of considering rare diagnoses in mediastinal masses.

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Last Updated: Jun 9, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
12:03

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016