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Updated: Jun 9, 2026

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
Published on: January 7, 2018
[Study of CO(2) pneumoperitoneum on the level of vWF in pregnancy rats]
1Department of Obstetric and Gynecology, Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China. zhangying5413@126.com
Aim:
The goal of this paper is to study changes of von Willebrand Factor in medium and late pregnancy rats' serum during diffencet time and pressure of CO(2) pneumoperitoneum.
Methods:
By solid phase phase sandwich enzyme linked immuno sorbent assay (ELISA).
Results:
(1) We succeed to build the model of carbon dioxide pneumoperitoneum in medium pregnancy rats. (2) The time and pressure of carbon dioxide pneumoperitoneum was proportional to von Willebrand Factor in serum, they have no statistical significance (P>0.05).
Conclusion:
It is safity to operate in medium pregnancy by laparoscopic surgery. But we must control the time in 2 hours.

