Related Experiment Video
Updated: Jun 9, 2026

A Burrowing/Tunneling Assay for Detection of Hypoxia in Drosophila melanogaster Larvae
Published on: March 27, 2018
[FOXO tanscription factor role in radiation adaptive response and hormisis in Drosophila melanogaster]
Abstract:
Previously we put forward a hypothesis about the role of FOXO-dependent mechanisms of stress-response gene activation after irradiation in radiation hormesis (Moskalev, 2008). To testify this assumption we analyze the influence of gamma-irradiation on duration of larvae development and imago lifespan in Drosophila strains with different FOXO function activity. We revealed that in FOXO hypomorphic allele homozygote strains the hormesis and adaptive response (increasing of larvae stage duration and longevity) were absent, in contrast to B wild type strain Canton-S and FOXO-heterozygotes.
More Related Videos
10:13Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM)
Published on: December 12, 2016
10:31The Drosophila Imaginal Disc Tumor Model: Visualization and Quantification of Gene Expression and Tumor Invasiveness Using Genetic Mosaics
Published on: October 6, 2016
Related Concept Videos
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Master Transcription Regulators