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Suppression of the PGO-related lumbar motoneuron IPSP by strychnine
F López-Rodríguez1, F R Morales, P J Soja
1Department of Physiology, University of California, Los Angeles 90024.
Brain Research
|December 10, 1990
Abstract:
Intracellular recordings from lumbar motoneurons in chronic unanesthetized cats revealed that a distinct inhibitory postsynaptic potential (IPSP) occurs following pontogeniculooccipital (PGO) waves during active sleep. Strychnine, when applied juxtacellularly by microiontophoresis, was found to block this IPSP. These data suggest that glycine is likely to be the neurotransmitter that is responsible for the inhibition of lumbar motoneurons that occurs in conjunction with the PGO waves of active sleep.