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Related Experiment Video

Updated: Jun 9, 2026

Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment

Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment

Published on: June 2, 2023

ICPS: an integrative cancer profiler system.

Xin-yu Zhang¹, Lin Shi, Yan Liu

¹State Key Laboratory of Intelligent Technology and Systems, Tsinghua National Laboratory for Information Science and Technology, Department of Computer Science and Technology, Tsinghua University, Beijing 100084, China. zhxy@mail.tsinghua.edu.cn

Bioinformatics (Oxford, England)

|August 26, 2010

Summary

The Integrative Cancer Profiling System (ICPS) identifies cancer biomarker profiles by analyzing genomic data and gene expression. This tool aids in cancer research and clinical diagnosis for 11 common cancers.

Related Experiment Videos

Last Updated: Jun 9, 2026

Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment

Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment

Published on: June 2, 2023

Area of Science:

Bioinformatics
Genomics
Cancer Research

Background:

The Integrative Cancer Profiling System (ICPS) is a web-based application.
It utilizes a database of 570 public signatures.
It integrates genomic alterations with transcription signatures.

Purpose of the Study:

To obtain biomarker profiles for 11 common cancers.
To support both public and user-provided in-house data.
To perform meta-analysis at a cancer subtype level.

Main Methods:

Integration of genomic alterations with transcription signatures.
Meta-analysis of heterogeneous datasets at the cancer subtype level.
Utilizes a previously developed integrative pipeline.

Main Results:

Identification of robust gene signatures for 11 common cancers.
Provides potential cancer biomarkers.
Facilitates analysis of user's in-house data.

Conclusions:

ICPS is a valuable tool for cancer research and clinical diagnosis.
The identified gene signatures may aid in understanding carcinogenesis.
The system supports comprehensive cancer profiling.