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Update on the causes, investigation and management of empyema in childhood
Woolf Walker1, Robert Wheeler, Julian Legg
1Regional Paediatric Respiratory Unit, Southampton University Hospitals NHS Trust, Southampton General Hospital, Tremona Road, Southampton, UK.
Insights
Childhood empyema management is debated. Current evidence supports antibiotics followed by chest drain with urokinase, reserving video-assisted thoracoscopic surgery for treatment failures.
Area of Science:
- Pediatrics
- Thoracic Surgery
- Infectious Diseases
Background:
- Childhood empyema, a serious pleural infection, has increasing incidence globally.
- Current management strategies for pediatric empyema lack universal consensus.
- Despite its long history, optimal treatment pathways remain under investigation.
Purpose of the Study:
- To review recent literature on the etiology and diagnosis of childhood empyema.
- To critically evaluate current treatment options for pediatric empyema.
- To propose a clinical practice guideline for empyema management.
Main Methods:
- Comprehensive literature search of recent studies on childhood empyema.
- Analysis of evidence regarding medical and surgical interventions.
- Development of a treatment algorithm based on reviewed data.
Main Results:
- Intravenous antibiotics are the initial step in management.
- Chest drain insertion with urokinase instillation is recommended as first-line treatment.
- Video-assisted thoracoscopic surgery (VATS) is indicated for cases unresponsive to initial medical therapy.
Conclusions:
- A structured approach to childhood empyema management is proposed.
- Early and appropriate intervention can improve outcomes.
- The proposed algorithm aims to standardize care and guide clinical decisions.
Abstract:
Despite being recognised for over two millennia and having an increasing incidence in many countries, the management of childhood empyema remains controversial. This review examines the recent literature on its causes and investigation then focuses on its treatment. Following a trial of appropriate intravenous antibiotics, the evidence would currently support the use of chest drain insertion with urokinase instillation as first line treatment with video-assisted thoracoscopic surgery to be used for failure of medical management. A treatment algorithm is proposed to guide clinical practice.
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