Related Experiment Video
Updated: Jun 9, 2026

A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit
Published on: November 21, 2023
Basic science of intra-articular fractures and posttraumatic osteoarthritis
Todd O McKinley1, Joseph Borrelli, Darryl D D'Lima
1Department of Orthopaedic Surgery, University of Iowa Hospitals, 200 Hawkins Drive, Iowa City, IA 52242, USA. Todd-mckinley@uiowa.edu
None:
Intra-articular fractures represent the primary etiologic factor leading to posttraumatic osteoarthritis. The pathomechanisms linking intra-articular fractures to end-stage cartilage destruction are poorly understood. However, fracture-related chondrocyte death has been linked to posttraumatic osteoarthritis. Researchers have made significant progress in understanding the pathomechanical link between injury and chondrocyte death. This article reviews recent basic scientific progress investigating intraarticular fractures and fracture-related chondrocyte death and dysfunction.
More Related Videos
Related Concept Videos
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
Structural Joints: Synovial Joints
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Degenerative Disc Disease ll: Pathophysiology

